. 2021 May 22;20:52. doi: 10.1186/s12944-021-01480-2

Table 4.

Multivariate multinomial regression analysis of risk factors for benign breast disease and breast cancer in relation to controls

Variable	Categories	Benign Breast Disease	P value	Breast cancer	P-value
Variable	Categories	AOR (95% CI)	P value	AOR (95% CI)	P-value
Age (years)	≥ 50	1.10 (0.41–2.95)	0.846	1.88 (0.41–8.58)	0.412
Age (years)	< 50	Ref		Ref
Menarche age (years)	< 12	1.29 (0.35–4.69)	0.702	0.43 (0.06–3.26)	0.415
Menarche age (years)	≥ 12	Ref		Ref
Menopause age (years)	> 46	0.83 (0.31–2.19)	0.706	1.42 (0.33–6.09)	0.640
Menopause age (years)	≤ 46	Ref		Ref
BMI (kg/m²)	≥ 23	1.29 (0.49–3.39)	0.594	53.65 (5.70–504.73)	< 0.001
BMI (kg/m²)	18.5- < 23	Ref		Ref
Total cholesterol (mg/ dL)	≥ 200	0.97 (0.29–3.24)	0.967	16.05 (3.13–82.29)	0.001
Total cholesterol (mg/ dL)	< 200	Ref		Ref
Low density lipoprotein (mg/ dL)	≥ 130	0.96 (0.34–2.67)	0.936	3.015 (0.63–14.51)	0.169
Low density lipoprotein (mg/ dL)	< 130	Ref		Ref
High-density lipoprotein (mg/ dL)	< 40	0.81 (0.28–2.34)	0.698	5.01 (0.98–25.52)	0.053
High-density lipoprotein (mg/ dL)	≥ 40	Ref		Ref
Triglyceride (mg/ dL)	≥ 150	1.21 (0.35–4.18)	0.758	1.63 (0.32–8.19)	0.552
Triglyceride (mg/ dL)	< 150	Ref		Ref

Data expressed as n(%) and mean ± SD where appropriate; AOR Adjusted Odds Ratio

*P-value significant at < 0.05 level in comparison to control and benign breast disease