Table 2.
Variable | Total (n = 259) |
Survivors (n = 67) |
Non-survivors (n = 192) |
P-value |
---|---|---|---|---|
ECMO (only) | 225 (86.9) | 55 (82) | 170 (89) | 0.18 |
Impella (only) | 12 (4.6) | 6 (9) | 6 (3) | 0.05 |
ECMO + Impella | 22 (8.5) | 6 (9) | 16 (8) | 0.88 |
Laboratory data upon arrival | ||||
pH | 6.90 [6.82–7.02] | 7.01 [6.92–7.15] | 6.88 [6.80–6.98] | < 0.001 |
Lactate (mmol/L) | 14.4 [11.4–17.0] | 12.0 [9.1–14.7] | 15.0 [12.0–19.0] | < 0.001 |
Potassium (mmol/L) | 4.4 [3.7–5.4] | 4.1 [3.6–4.9] | 4.6 [3.8–5.5] | 0.06 |
Hemoglobin (mmol/L) | 8.6 [7.5–9.6] | 8.7 [8.1–9.6] | 8.6 [7.3–9.6] | 0.22 |
Creatinine (mmol/L) | 114 [98–130] | 109 [95–131] | 115 [99–130] | 0.86 |
CAG performed | 234 (90) | 62 (93) | 172 (90) | 0.48 |
Coronary intervention (PCI/stent) | 124 (48) | 37 (55) | 87 (46) | 0.20 |
Left main | 22 (9) | 5 (8) | 17 (10) | 0.73 |
Left anterior descending | 76 (33) | 27 (44) | 49 (29) | 0.02 |
Left circumflex | 8 (3) | 2 (3) | 6 (4) | 0.96 |
Right coronary artery | 30 (13) | 9 (15) | 21 (12) | 0.58 |
Intensive care stay | ||||
No. of patients admitted to ICU | 218 (84) | 67 (100) | 151 (79) | < 0.001 |
TTM | 152 (70) | 46 (69) | 106 (70) | 0.46 |
Renal replacement therapy | 91 (42) | 32 (48) | 59 (31) | 0.27 |
ICU length of stay (hours) | 53 [13–238] | 284 [163–528] | 19 [10–63] | < 0.001 |
ECPR-/Impella-related complications | ||||
Bleeding at cannulation site | 76 (29) | 32 (48) | 44 (23) | 0.01 |
Limb ischemia | 24 (9) | 5 (8) | 19 (10) | 0.31 |
Gastrointestinal bleeding | 33 (13) | 10 (15) | 23 (12) | 0.90 |
Gastrointestinal ischemia | 22 (9) | 4 (6) | 18 (9) | 0.20 |
Time on ECPR (hours) | 50 [27–95] | 67 [40–98] | 37 [8–77] | 0.002 |
Time on Impella (hours) | 74 [28–165] | 62 [50–165] | 84 [10–166] | 0.46 |
Hospital length of stay (hours) | 23 [7–358] | 687 [496–1060] | 13 [4–46] | < 0.001 |
Abbreviations: ECMO Extracorporeal membrane oxygenation; CAG Coronary angiogram; PCI Primary coronary intervention; ICU Intensive care unit; TTM Target temperature management
Values are stated as medians and interquartile range (IQR) or numbers and percentages. A p- value of < 0.05 is considered significant