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. 2021 May 22;18:19. doi: 10.1186/s12950-021-00286-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Nuclear and cytoplasmic AIM2. Representative confocal images revealing nuclear and cytoplasmic AIM2 detected with a rabbit polyclonal antibody (a, aa250–300/354, red by AF594) and a mouse monoclonal antibody (b, aa1–159, pseudogreen by AF647) in the same paraffin section of a human lung biopsies. Boxed areas are shown at magnification (right) to reveal cells having predominantly nuclear AIM2 (top box), or both nuclear and cytoplasmic AIM2 (bottom box). Blue is DAPI. Nuclear localization of AIM2 is indicated by the merged colors magenta in A and azure in B. Scale bars are in micrometers