Table 5.
Multiple regression analysis of intraoperative outcomes, postoperative complication rates, and biochemical markers of systemic inflammation in RCS and LCS surgery for colorectal cancer. Represented values of regression analysis for LCS where RCS is the reference value. All analyses were adjusted for T-stage, ASA-score, neoadjuvant chemotherapy, BMI, age, type of resection (colonic or rectal), and temporary diverting ileostomy formation. OR odds ratio, CI confidence interval, IRR incidence rate ratio, EC exponentiated coefficient
| Variable | Coefficient | 95% CI | P-value | |
|---|---|---|---|---|
| RCS (n = 143) | LCS (n = 155) | |||
| Surgical complication rate (OR, 95%CI) | 1 | 1.51 | 0.69–3.29 | 0.300a |
| Medical complication rate (OR, 95%CI) | 1 | 0.97 | 0.51–1.87 | 0.941a |
| Intraoperative blood loss (IRR, 95%CI) | 1 | 1.78 | 1.35–2.35 | < 0.001b |
| Operative time (IRR, 95%CI) | 1 | 0.98 | 0.97–0.99 | 0.005c |
| Length of stay (IRR, 95%CI) | 1 | 1.12 | 1.02–1.24 | 0.018c |
| Time to first flatus (IRR, 95%CI) | 1 | 1.01 | 0.84–1.21 | 0.933c |
| Time to first stool (IRR, 95%CI) | 1 | 1.01 | 0.87–1.17 | 0.935c |
| Harvested lymph nodes (IRR, 95%CI) | 1 | 0.91 | 0.88–0.95 | < 0.001c |
| CRP (EC, 95%CI) | 1 | 1.23 | 1.06–1.44 | 0.008d |
| Leukocytes (EC, 95%CI) | 1 | 1.04 | 0.98–1.11 | 0.177d |
aOrdinal logistic regression
bNegative binomial regression
cPoisson regression
dMultilevel mixed effect linear regression