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. 2021 May 19;14:3297–3307. doi: 10.2147/OTT.S288442

Figure 4.

Figure 4

BXXX inhibits the proliferation and promotes the apoptosis of GC cells by indirectly regulating the expression of PD-L1 through multiple pathways and targets. (A) CCK-8 detected the cell viability. (B) Tunel assay detected the apoptosis of cells. (C) Western blot detected the expression of related proteins in the PD-L1 pathway. (D) Western blot detected the expression of EGFR, IFNGR and TLR4 in cell membrane. *P<0.05, **P<0.01, ***P<0.001 vs NC. Control group: cells were cultured in normal medium; NC group: cells were cultured in BXXX-free rat serum; BXXX-5%: cells were cultured in BXXX-5% rat serum; BXXX-10%: cells were cultured in BXXX-10% rat serum; BXXX-20%: cells were cultured in BXXX-20% rat serum.