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. 2021 Jan 27;384(2):499–511. doi: 10.1007/s00441-020-03398-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Localization of CXCL11 expression in developing and adult limb muscles. Sections were obtained from the quadriceps muscle of E18 a, b and adult rats c, d and double-labelled with antibodies against CXCL11 (red) and MyHC (green). Cell nuclei were visualized with DAPI. At each developmental stage, first row a, c and second row b, d show low and high magnification, respectively. a″–d″ Merging of immunocytochemical stainings and DAPI. In E18 muscles, CXCL11-immunolabelling was associated with many muscle fibres (arrows in a″). Higher magnification b″ confirmed the predominant intracellular localization of CXCL11 at this developmental stage. In adult muscles, CXCL11 expression was confined to cells within the endomysium/perimysium (arrow heads in d). Scale bars, a and c, 100 µm; b and d, 25 µm