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. 2021 May 10;13:659898. doi: 10.3389/fnagi.2021.659898

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Copyright © 2021 Gleerup, Sanna, Høgh, Simrén, Blennow, Zetterberg, Hasselbalch, Ashton and Simonsen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Box plots of neurofilament light chain levels in saliva and plasma and the normalized levels of saliva NfL. (A) The boxplots show the median, interquartile range, and the extreme values of salivary NfL for HC, MCI, AD, and non-AD. The 2.5–97.5 percentile of all data had been included in the boxplots. (B) The boxplots show the median, interquartile range, and the extreme values of the normalized levels of salivary NfL for HC, MCI, AD, and non-AD. The 2.5–97.5 percentile of all data had been included in the boxplots. (C) The boxplots show the median, interquartile range, and the extreme values of plasma NfL for HC, MCI, AD, and non-AD. The 2.5–97.5 percentile of all data had been included in the boxplots. NfL, neurofilament light chain; HC, healthy controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease.