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. 2021 May 10;11:640467. doi: 10.3389/fonc.2021.640467

Table 4.

Acute and late GI and GU toxicity (≥grade 2) by treatment volume concept according to CTCAE v4.03.

Toxicity Acute toxicity
  PDRT n (%)   PDRT + eRT n (%)  
  Grade 2 Grade 3 Grade 2 Grade 3
GU 2 (1.3) 0 31 (13.2) 0
GI 12 (7.5) 0 43 (18.3) 1 (0.4)
Other 0 0 0 1 (0.4)
Late toxicity
  PDRT n (%) PDRT + eRT n (%)  
  Grade 2 Grade 3 Grade 2 Grade 3
GU 1 (0.6) 0 35 (14.9) 7 (3.0)
GI 2 (1.3) 0 10 (4.3) 0
Other 0 0 0 0

PDRT, PET/CT-directed radiotherapy; eRT, elective radiotherapy.