TABLE 5.

Regions identified by both rare and all variants analysis in a particular population after Bonferroni adjustment.

Population	Chro	Regions	Gene	Rare variants analysis			All variants analysis
				p-value in this population	Fisher’s p-value	# of SNPs in region	p-value in this population	Fisher’s p-value	#of SNPs in region
Illumina	1	21,069,170–21,113,181	HP1BP3	7.97 × 10–11	3.65 × 10–8	224	8.03 × 10–11	2.54 × 10–7	296
	3	48,445,260−48,471,460	PLXNB1	5.82 × 10–8	7.17 × 10–6	155	5.82 × 10–8	1.43 × 10–5	187
	3	49,506,135–49,573,051	DAG1	5.80 × 10–11	3.83 × 10–7	169	5.99 × 10–8	6.37 × 10–5	304
	17	5,015,229–5,017,677	LOC101928000	1.20 × 10–6	4.25 × 10–5	78	1.14 × 10–6	1.72 × 10–4	119
	17	5,019,732–5,078,326	USP6	3.11 × 10–7	1.31 × 10–4	253	2.92 × 10–7	3.43 × 10–5	406
Human Core	12	56,512,003–56,516,280	ZC3H10	9.95 × 10–7	1.37 × 10–4	54	1.05 × 10–6	1.16 × 10–4	71
	12	56,521,985–56,538,460	ESYT1	1.14 × 10–6	1.68 × 10–4	102	1.16 × 10–6	1.66 × 10–4	122
	12	56,546,203–56,551,771	MYL6B	6.04 × 10–7	7.77 × 10–5	61	6.04 × 10–7	9.85 × 10–5	76
	12	56,660,641–56,664,750	COQ10A	5.68 × 10–7	9.10 × 10–5	27	1.38 × 10–6	5.74 × 10–4	53
	12	57,623,355–57,628,718	SHMT2	1.57 × 10–7	2.49 × 10–5	70	1.57 × 10–7	2.49 × 10–5	86
	12	57,628,685–57,634,475	NDUFA4L2	1.90 × 10–7	2.81 × 10–5	52	1.90 × 10–7	2.81 × 10–5	66
	12	57,637,237–57,644,976	STAC3	7.88 × 10–8	1.23 × 10–5	55	7.88 × 10–8	1.23 × 10–5	70
	12	57,647,546–57,824,788	R3HDM2	1.96 × 10–7	1.10 × 10–5	501	1.96 × 10–7	1.11 × 10–5	729
	12	57,828,467–57,845,845	INHBC	1.06 × 10–6	2.94 × 10–5	85	1.06 × 10–6	2.94 × 10–5	133