Figure 1.

Remote ischemic conditioning increases the oxygen supply to ischemic brain tissue. (a) The average hypoxic areas (%) of all mice between the two groups (6 mice per group) were compared by the Student’s t-test. The hypoxic area was calculated using the following formula: [area of nonischemic hemisphere (hypoxyprobe negative) − area of the hypoxyprobe negative region in the ischemic hemisphere]/2 × area of nonischemic hemisphere × 100%. (b) The average hypoxic intensities of all mice between the two groups were compared by the Student’s t-test. (c) Representative images at the same level (brain optic chiasm level) of brain from each group were depicted. **p < 0.01, ***p < 0.001. The findings were similar when the same experiment was repeated twice independently.