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. 2020 Oct 13;41(6):1313–1327. doi: 10.1177/0271678X20962594

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Figure 4. — K_IR2.1 channel current density is markedly reduced in ECs isolated from TBI mice. Inwardly rectifying current (black) was evoked by a 400-ms voltage ramp (−140 to +40 mV; lower inset) in capillary endothelial cells isolated from control (a) and TBI (b) mice and blocked by 100 μM Ba²⁺. (c) Summary data of Ba²⁺-sensitive current density at peak inward currents (−140 mV) in control (−11 ± 2 pA/pF, n = 8 cells, from 3 mice) and TBI mice (−4 ± 1 pA/pF, n = 11 cells, from 4 mice) (*p < 0.0001, Mann-Whitney test). Data are expressed as mean ± SD.