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. Author manuscript; available in PMC: 2021 May 24.
Published in final edited form as: Environ Mol Mutagen. 2017 Nov 9;59(2):103–113. doi: 10.1002/em.22151

Fig. 2.

Fig. 2.

Comparison of BMD values for WSSs in the mouse lymphoma assay. The BMD (BMD10, BMD50, BMD100, and BMD200) estimates producing a 10%, 50%, 100%, or 200% increase in the background frequency were calculated using exponential model of PROAST both without (A,B,C,D) and with covariate analysis approach (E,F,G,H). The bars represent the calculated 95% confidence interval of each value. The lower and upper limits derived from the BMD estimates were used to differentiate between responses based on non-overlapping confidence intervals.