Table 2. Force transients in intact PMs from the hearts of RCM-E143K versus WT-ELC mice.

Parameter	WT	HCM-A57G	Δ43	RCM-E143K
Number of animals	11 (7 M, 4 F)	8 (5 M, 3 F)	6 (3 M, 3 F)	8 (3 M, 5 F)
t25 relax (ms)	57.2 ± 7.7	48.6 ± 5.2a	61.8 ± 5.3b	69.3 ± 7.4a,c
t50 relax (ms)	92.6 ± 11.5	78.1 ± 8.6a	98.8 ± 11.0b	111.8 ± 13.9a,c
t75 relax (ms)	136.5 ± 16.0	115.8 ± 17.3	148.3 ± 17.90b	166.8 ± 21.0a,c
Force/area (mN/mm2)	0.42 ± 0.27	0.34 ± 0.23	0.24 ± 0.13	0.39 ± 0.16

Data are mean ± SD. P values were calculated with one-way ANOVA with Tukey’s multiple comparison test. For comparisons between the RCM, HCM, and Δ43 phenotypes, the data for HCM-A57G and Δ43 animals (columns 3 and 4) were taken, with permission, from Sitbon et al. (2020).

^aP < 0.05 for mutant versus WT-ELC.

^bP < 0.05 for Δ43 versus A57G.

^cP < 0.05 for E143K versus A57G.