Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 10;12:665987. doi: 10.3389/fendo.2021.665987

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Albhaisi and Sanyal

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

PNPLA3 ^I148M-associated acceleration of NASH and fibrosis. (A) Liver histology in mouse of empty vector (Luc) after 16 weeks on a Western diet/sugar water (WDSW) diet with NAFLD with minimal fibrosis. (B) Hepatocyte of mouse with PNPLA3 ^I148M after 16 weeks on a WDSW diet demonstrating NAFLD with advanced bridging fibrosis. (A) 16wks AAV LUC (10x) (B) 16wks PNPLA3 I148M (4x).