Table 1.
Proposed threshold values for heart failure diagnosis in various clinical conditions.
| Proposed Threshold Values for Heart Failure Diagnosis in Various Clinical Conditions (with Reference Number) | BNP (pg/ml) | NT proBNP (pg/ml) | Values below threshold exclude heart failure; patients with higher values need echocardiography to confirm the diagnosis. |
|---|---|---|---|
| Acute onset of dyspnea [1] | 100 | 300 | |
| Progressive onset of dyspnea [1] | 35 | 125 | |
| Atrial fibrillation [48] [49] |
- | 1100 | |
| 490 | 3460 | ||
| Chronic kidney disease GFR>60ml/min/1.73 m2 [53] |
100 | 450 for pts below 50 years 900 for pts above 50 years |
|
| GFR ≤60ml/min/1.73 m2 [53] | 200 | 1200 | |
| Septic shock [55] | - | 1200 | |
| COPD exacerbation [57] | - | 1077 | |
| Prognosis threshold values | |||
| Chronic heart failure [22] | Increase with 100 pg/ml | Above 550 | Higher values correlate with increased mortality |
| Pulmonary embolism [45] | 75-100 | 600 | |
| Acute myocardial infarction [47] | 80 | 1170 for men 2150 for women |