Table 3.
Author | Number of Patients | Methods | Time scale | Result |
---|---|---|---|---|
Komaru et al. [114] | 13 | Patients treated with POBA for stable angina. Measured vasomotion with IC substance P |
Measured the day after angioplasty and three months afterwards | The “day after” there was a vasoconstrictor response. More uniform vasodilator response after three months |
Vassanelli et al. [58] | 25 | Patients treated with POBA assessed with IC ACH | Three months and six months after treatment | Abnormal vasomotor responses at both three and six months |
Caramori et al. [115] | 39 | Post-treatment to their LAD artery with POBA and BMS with IC ACH | Six months | Significantly greater vasoconstrictor responses with BMS vs. POBA (-21.8% ± 4.3 vs. -9.5% ± 2.8, p=0.02) |
Togni et al. [116] | 25 | Treated 11 with BMS and 14 with SES Angiography during exercise |
Six months | Exercise-induced vasoconstriction in SES compared with BMS |
Kim et al. [28] | 78 | 10 received BMS, 36 received PES, and 39 DES assessed with IC ACH. Measured responses within stents as well as proximally and distally | Six months | Vasoconstriction with DES even proximally and distally that was worse than BMS |
Gomez-Lara et al. [109] | 59 | Non-diabetic patients randomised to either BVS or Everolimus DES measured response to IC ACH | 13 months | More pronounced in scaffold vasoconstriction in BVS than DES |
MAGSTEMI [109] | 69 | STEMI patients treated with BVS vs. SES | 12 months | More pronounced vasoconstrictive response with BVS vs. SES |
Abbreviations: BMS = Bare Metal Stents; BVS = Bioresorbable Vascular Scaffolds; IC ACH = Intracoronary Acetylcholine; PES = Paclitaxel Eluting Stents; SES = Sirolimus Eluting Stents.