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. 2021 Jan;17(1):85–100. doi: 10.2174/1573403X16666200618161942

Table 3.

Comparison of the studies looking at vasomotion in patients treated with PCI.

Author Number of Patients Methods Time scale Result
Komaru et al. [114] 13 Patients treated with POBA for stable angina.
Measured vasomotion with IC substance P
Measured the day after angioplasty and three months afterwards The “day after” there was a vasoconstrictor response. More uniform vasodilator response after three months
Vassanelli et al. [58] 25 Patients treated with POBA assessed with IC ACH Three months and six months after treatment Abnormal vasomotor responses at both three and six months
Caramori et al. [115] 39 Post-treatment to their LAD artery with POBA and BMS with IC ACH Six months Significantly greater vasoconstrictor responses with BMS vs. POBA
(-21.8% ± 4.3 vs. -9.5% ± 2.8, p=0.02)
Togni et al. [116] 25 Treated 11 with BMS
and 14 with SES
Angiography during exercise
Six months Exercise-induced vasoconstriction in SES compared with BMS
Kim et al. [28] 78 10 received BMS, 36 received PES, and 39 DES assessed with IC ACH. Measured responses within stents as well as proximally and distally Six months Vasoconstriction with DES even proximally and distally that was worse than BMS
Gomez-Lara et al. [109] 59 Non-diabetic patients randomised to either BVS or Everolimus DES measured response to IC ACH 13 months More pronounced in scaffold vasoconstriction in BVS than DES
MAGSTEMI [109] 69 STEMI patients treated with BVS vs. SES 12 months More pronounced vasoconstrictive response with BVS vs. SES

Abbreviations: BMS = Bare Metal Stents; BVS = Bioresorbable Vascular Scaffolds; IC ACH = Intracoronary Acetylcholine; PES = Paclitaxel Eluting Stents; SES = Sirolimus Eluting Stents.