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. 2021 May 22;16(1):482–494. doi: 10.1515/biol-2021-0030

Figure 1.

Figure 1

Circ_0013359 expression is increased in melanoma tissues and cells. (a) The schematic diagram showed the cyclization of circ_0013359. (b) Expression of circ_0013359 in melanoma tissues (n = 30) and adjacent normal tissues (n = 30) was determined by qRT-PCR. (c) Circ_0013359 level was measured in HEMn-LP, A875, and SK-MEL-1 cells. (d and e) After RNase R treatment, qRT-PCR was used to detect the levels of circ_0013359 and linear COL11A1. (f and g) The levels of circ_0013359 and COL11A1 mRNA were detected in A875 and SK-MEL-1 cells transfected with si-NC or si-circ_0013359. *P < 0.05.