. Author manuscript; available in PMC: 2021 May 24.

Published in final edited form as: J Parkinsons Dis. 2020;10(2):489–504. doi: 10.3233/JPD-191853

Table 1.

Summary of ventilatory variables, abbreviations, units, and general findings

Variable	Abbreviation	Unit	Summary of Significant Findings
			Baseline	Hypoxia	MCS
Breathing frequency	F	breaths/min	Increased in Pink1−/−	Decrease over time	Decreased from 4 to 10 mo in Pink1−/−
			Decrease over time		No changes in WT
Inspiratory time	T_I	s
Expiratory time	T_E	s
Tidal volume	V_T	mL/100 g	Decreased in Pinkl−/−	Decrease over time	Decrease over time
			Decrease over time
Minute ventilation	(F × V_T) = V_E	mL/min/100g	Decrease over time	Decrease over time	Decrease over time
Peak inspiratory frequency	PIF		Increase over time	Increase over time	Increase over time
Peak expiratory frequency	PEF		Increase over time	Increase over time	Increase over time
Mean inspiratory flow	V_T/T_I	mL/s/100g	Decrease over time	Decrease over time	Decrease over time