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. 2021 Jan 15;80(6):727–738. doi: 10.1136/annrheumdis-2020-219213

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Change in modified total Sharp/van der Heijde score (mTSS) and components from baseline at (A) week 24 and (B) week 52. ***Exploratory p<0.001; **exploratory p<0.01; *exploratory p<0.05; for supportive analysis without adjustment for multiplicity. Error bars represent 95% CI. For mTSS, week 24 includes only data from campaign A and week 52 includes data from campaign A and B. Week 52 n values are not provided for mTSS change from baseline, as the analysis included both campaign A (through week 24) and campaign B (through week 52 including re-reading of baseline and week 24). ES, erosion score; FIL, filgotinib; JSN, joint space narrowing; LSM, least-squares mean; MTX, methotrexate.