Skip to main content
. 2021 Feb 18;80(6):714–726. doi: 10.1136/annrheumdis-2020-219247

Figure 8.

Figure 8

Scoring of bone erosions in arthritic joints. (A) Representative images from TRAP-stained sections indicating severity scores of bone erosions in small tarsal joints graded from 0 (none) to 3 (severe). Here, erosions are exemplified on sagittal tarsal sections from 8-week-old wild-type and 8-week-old to 12-week-old Tg197 mice. (B) Marked areas defining bone erosion from the same images (blue fields). (C) Labelling of bone erosion in larger bones such as tibia (tibiotalar joint) in HE-stained sections from CIA model (days 35 and 42 after immunisation). (D) Description of characteristic features defining grading scores of local bone erosion from 0 to 3 in the affected joints. Original magnification is 200×. CIA, collagen-induced arthritis; TRAP, tartrate-resistant acid phosphatase.