Table 5.
Multivariate Cox regression analyses of variables associated with de novo CKD within postoperative one year
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (years) | 1.032 | 1.009–1.056 | 0.001 | 1.036 | 1.011–1.062 | 0.005 |
| BMI | 1.011 | 0.924–1.106 | 0.810 | |||
| Sex, male | 0.711 | 0.348–1.454 | 0.350 | |||
| DM | 1.295 | 0.646–2.595 | 0.466 | |||
| HTN | 2.413 | 1.353–4.304 | 0.003 | 2.159 | 1.233–3.783 | 0.007 |
| Baseline eGFR | 0.992 | 0.982–1.003 | 0.150 | |||
| Baseline Hb | 0.986 | 0.875–1.112 | 0.822 | |||
| EBL (1st surgery) | 1.000 | 0.999–1.001 | 0.799 | |||
| EBL (2nd surgery) | 1.000 | 0.999–1.001 | 0.663 | |||
| Ischemic time (1st surgery) | 1.005 | 0.974–1.037 | 0.763 | |||
| Ischemic time (2nd surgery) | 0.987 | 0.957–1.019 | 0.431 | |||
| Pathologic tumor size (1st surgery) | 1.015 | 1.006–1.024 | 0.001 | 1.012 | 1.003–1.021 | 0.010 |
| Pathologic tumor size (2nd surgery) | 1.004 | 0.996–1.011 | 0.326 | |||
| Time between operations | 1.000 | 1.000–1.001 | 0.083 | |||
| Surgery sequence | ||||||
| PN ➔ PN | Reference | Reference | ||||
| PN ➔ RN | 2.249 | 1.088–4.786 | 0.006 | 1.837 | 1.028–3.635 | 0.007 |
| RN ➔ PN | 1.510 | 1.096–5.750 | 0.030 | 1.235 | 0.947–5.276 | 0.066 |
| PN (unilateral case) | 0.663 | 0.285–1.543 | 0.341 | 0.315 | 0.119–0.832 | 0.261 |
| Tumor chronology | ||||||
| Synchronous | Reference | |||||
| Metachronous | 1.370 | 0.660–2.840 | 0.398 | |||
| Tumor multiplicity | ||||||
| Unilateral | Reference | |||||
| Bilateral | 1.244 | 0.698–2.215 | 0.459 | |||