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. 2020 May 29;11:1178122X20913274. doi: 10.1177/1178122X20913274

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Evolution of herpes and humans. Schematic representation of a phylogenetic tree showing approximate dates known for common ancestors shared between humans and primates. Tree branches represent evolution of distinct species. Evidence suggests HSV infected a common ancestor and then coevolved with each host species, giving rise to HSV-1 in humans. HSV-2 arose due to cross-species transmission that occurred more recently, when early hominids were infected with ChHV. ChHV indicates chimpanzee herpesvirus; HSV, herpes simplex virus.