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. 2021 May 24;108:282–288. doi: 10.1016/j.ijid.2021.05.048

Table 4.

Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of high COVID-GRAM scores and CURB-65 scores ≥2 in predicting critical illness and 30-day mortality in 523 patients hospitalized with COVID-19.

(TP/total positives) (TN/total negatives) Sensitivity (%) Specificity (%) PPV (%) NPV (%)
(95% CI) (95% CI) (95% CI) (95% CI)
Critical illness
High COVID-GRAM score 59/122 51/401 0.53 (0.44–0.62) 0.84 (0.81–0.88) 0.48 (0.39–0.57) 0.87 (0.84–0.91)
CURB-65 score ≥2 71/197 39/326 0.64 (0.55–0.73) 0.69 (0.65–0.73) 0.36 (0.29–0.43) 0.88 (0.85–0.92)
30-day mortality
High COVID-GRAM score 56/122 385/401 0.77 (0.68–0.87) 0.85 (0.82–0.88) 0.46 (0.37–0.55) 0.96 (0.94–0.98)
CURB-65 score ≥2 62/197 10/316 0.86 (0.78– 0.94) 0.70 (0.64–0.75) 0.31 (0.25–0.38) 0.97 (0.95–0.99)

CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive.