. 2021 May 20;10(6):26. doi: 10.1167/tvst.10.6.26

Table 3.

Validation of Single and Aggregated Measures of Tortuosity in Corneal Nerve Images From Grade I to Grade IV

Grades	Grade I	Grade II	Grade III	Grade IV	F	P
LC (*10⁻³), mean (SD)	43.71 (25.44)	55.89 (29.66)^‡	69.23 (28.36)^‡^,^§	94.02 (35.65)^‡^,^§^,^\|\|	156.792	<0.001
Cur_max (*10⁻³), mean (SD)	43.60 (10.87)	46.52 (9.01)^†	49.82 (9.38)^‡^,^§	54.93 (9.98)^‡^,^§^,^\|\|	89.579	<0.001
TC (*10⁻³), mean (SD)	10.44 (1.94)	11.85 (1.76)^‡	12.92 (1.94)^‡^,^§	14.52 (2.30)^‡^,^§^,^\|\|	246.895	<0.001
TSC (*10⁻⁵), mean (SD)	20.89 (8.89)	26.13 (8.13)^‡	31.54 (10.78)^‡^,^§	40.29 (13.23)^‡^,^§^,^\|\|	206.890	<0.001
DCI (*10⁻⁶), mean (SD)	17.23 (10.84)	22.35 (11.12)^‡	28.88 (16.10)^‡^,^§	38.90 (19.75)^‡^,^§^,^\|\|	123.941	<0.001
ICM (*10⁻¹), mean (SD)	7.07 (4.06)	7.56 (4.22)^#	8.96 (5.31)^‡^,^§	11.20 (6.79)^‡^,^§^,^\|\|	24.032	<0.001
Tagg (*10⁻²), mean (SD)	14.95 (9.69)	19.82 (8.38)^‡	25.37 (10.67)^‡^,^§	34.06 (12.22)^‡^,^§^,^\|\|	220.699	<0.001

One-way ANOVA was applied to test differences among the four groups. Tamhane's T2 test was applied as a post-hoc multiple comparisons test for pairwise comparison.

^†

P < 0.01, compared with Grade I.

^‡

P < 0.001, Compared with Grade I.

^§

P < 0.001, Compared with Grade II.

^||

P < 0.001, Compared with Grade III.

P ≥ 0.05, Compared with Grade III.