Fig. 1. Light-induced photocleavage reaction of the NPOM group from DNA. (Top) Schematic of the photocleavage reaction. Upon light irradiation (λ = 365 nm or 405 nm), the NPOM group (orange) is cleaved from the modified thymidine (dT) in the DNA, restoring unmodified thymidine while releasing nitrosoacetophenone. (Bottom) Cartoon of the photocleavage reaction in NPOM-containing duplexed DNA.
