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Aerosol drug delivery to the level of the trachea with two nebuliser types e.g., vibrating mesh nebuliser (VMN) in combination with a mouthpiece and no supplemental flow and jet nebuliser (JN) with open facemask at 7 L per minute compressed air flow rate during spontaneous breathing (SB). The values represented are the mean averages ± SD of five independent experiments. Differences were considered statistically significant when * p ≤ 0.05.
