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. 2021 Apr 21;11(5):524. doi: 10.3390/brainsci11050524

Table 1.

Participant characteristics at the 10-month and 3-year laboratory visits.

10-Month Visit
FH-ADHD FH-ADHD
and ASD
FH-ASD FH-No ADHD/ASD
N 27 20 77 27
Age (days) M (SD) 324 (28) 320 (15) 320 (15) 322 (17)
Range 278–384 300–354 287–357 293–358
Sex 12 female 8 female 38 female 11 female
15 male 12 male 39 male 16 male
Highest education level of primary caregiver a 8 Secondary
10 Undergraduate
9 Postgraduate
11 Secondary
6 Undergraduate
2 Postgraduate
1 Primary
18 Secondary
38 Undergraduate
18 Postgraduate
2 Secondary
10 Undergraduate
14 Postgraduate
MSEL ELC b
M (SD) 85.04 (15.61) 84.90 (16.55) 88.03 (15.09) 88.89 (12.19)
Range 61–128 59–134 50–136 58–114
3-Year Visit
FH-ADHD FH-ADHD
and ASD
FH-ASD FH-No ADHD/ASD
N c 21 14 57 21
Age (months)
M (SD) 37.42 (2.93) 37.21 (1.63) 37.00 (1.17) 36.83 (1.82)
Range 36–49 36–41 36–42 35–43
Sex 9 female 4 female 30 female 9 female
12 male 10 male 27 male 12 male
Highest education level of primary caregiver d 5 Secondary
8 Undergraduate
8 Postgraduate
7 Secondary
4 Undergraduate
2 Postgraduate
1 Primary
14 Secondary
29 Undergraduate
11 Postgraduate
1 Secondary
7 Undergraduate
12 Postgraduate
MSEL ELC
M (SD) 118.58 (20.37) 106.00 (20.65) 107.27 (19.24) 129.94 (11.41)
Range e 66–144 65–131 75–141 109–146

a Data missing for 4 participants (2 FH-ASD; 1 FH-No ADHD/ASD; 1 FH-ADHD and ASD). b Further information regarding MSEL administration is provided in SM3. Data is missing for one participant in the FH-ADHD group, and one participant in the FH-ASD group. c Demographics at 3 years are presented only for participants who had both valid data at the 10-month time point and data on the ADHD subscale of the CBCL at 3 years. Data at 3 years also includes three children with a half-sibling with ADHD. These infants were not included in the primary 10-month analyses due to not meeting eligibility criteria for the FH-ADHD group or the FH-No ADHD/ASD group. However, they were included in the longitudinal analyses. For these participants at 3 years, Age M (SD) = 37.33 (2.31); Sex = 3 male; Highest education of primary caregiver = 3 Secondary; MSEL ELC M (SD) = 99.67 (44.29). d Data missing for 4 participants (2 FH-ASD; 1 FH-No ADHD/ASD; 1 FH-ADHD and ASD). Data was collected at the 10-month timepoint. e Data missing for 11 participants (2 FH-ADHD; 6 FH-ASD; 3 FH-No ADHD/ASD). MSEL; Mullen Scales of Early Learning. The MSEL (Mullen, 1995) is a standardized measure that assesses developmental abilities across five subscales including: Fine Motor, Gross Motor, Visual Reception, Receptive Language and Expressive Language. FH, Family History; ADHD, Attention Deficit Hyperactivity Disorder; ASD, Autism Spectrum Disorder; ELC, Early Learning Composite.