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. 2021 May 10;12:618037. doi: 10.3389/fendo.2021.618037

Figure 1.

Figure 1

Effects of emodin on body weight, food intake and Lee’s index in HFD mice. Mice were fed with high fat diet (HFD) containing 5.24 kcal/g for 8 weeks to induce hyperlipidemia. The mice in HFD+Emo group were intragastrically administered with emodin at the doses of 40 and 80 mg/kg/day respectively for consecutive 6 weeks. The mice in HFD+CL 316243 group were intraperitoneally injected with 1mg/kg/day of CL 316243 disodium salt for 3 days just before detecting time point. (A) Body weight. (B) Food intake. (C) Lee’s index. (D) The ratio of scWAT mass/BW. (E) The ratio of BAT mass/BW. HFD, high fat diet; Emo, emodin. Data are expressed as mean ± SE, with n = 8. * P < 0.05, ** P < 0.01 vs. HFD group.