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. 2021 May 10;12:618037. doi: 10.3389/fendo.2021.618037

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Copyright © 2021 Cheng, Zhang, Shang, Ning, Huang, He, Sun and Dong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of emodin on the morphology and function of BAT in HFD mice. (A) H&E and immunohistochemical staining of BAT. (B) Relative expression of UCP1 in BAT. (C) Relative expression of prohibitin in BAT. (D) Protein expression of UCP1, prohibitin, PPAR α, CD36 and FATP4 in BAT using western blotting. (E) Protein expression of UCP1. (F) Protein expression of prohibitin. (G) Protein expression of PPAR α. (H) Protein expression of CD36. (I) Protein expression of FATP4. HFD, high fat diet; Emo, emodin. Data are expressed as mean ± SE. ^* P < 0.05, ^** P < 0.01 vs. HFD group.