Table 3.
Stratified prospective analyses of the association of plasma vitamin C with risk of graft failure.
| Models | Plasma Vitamin C | ||
|---|---|---|---|
| Tertiles | |||
| Tertile 1 | Tertile 2 | Tertile 3 | |
| Ref. | HR (95% CI) | HR (95% CI) | |
| Triglycerides (pinteraction = 0.01) | |||
| <1.9 mmol/L (nevents = 38) | 1.00 | 0.38 (0.18–0.79) | 0.10 (0.03–0.36) |
| ≥1.9 mmol/L (nevents = 37) | 1.00 | 1.18 (0.49–2.56) | 1.97 (0.79–4.89) |
| HDL (pinteraction = 0.04) | |||
| <0.91 mmol/L (nevents = 37) | 1.00 | 0.79 (0.35–1.79) | 2.09 (0.84–5.17) |
| ≥0.91 mmol/L (nevents = 38) | 1.00 | 0.51 (0.24–1.05) | 0.17 (0.05–0.51) |
Cox proportional-hazards regression analyses were performed to assess the association of plasma vitamin C concentration with risk of graft failure (nevents = 75). Associations are shown with plasma vitamin C concentration as a continuous variable and according to tertiles of the vitamin C distribution (tertile 1, n = 197: <35 µmol/L; tertile 2, n = 202: 35‒51 µmol/L; tertile 3, n = 199: ≥51 µmol/L), with adjustment for age, sex, body mass index, donor age, donor sex, eGFR, and proteinuria.