ACR	American College of Rheumatology
ANCA	anti-neutrophil cytoplasm autoantibody
C3	complement 3
C4	complement 4
DHR123	dihydrorhodamine 123
eQTL	expression quantitative trait loci
fMLP	N-formyl-methionyl-leucyl-phenylalanine
FS	fluorescence signal
GAPDH	glyceraldehyde-3-phosphate dehydrogenase
GWAS	genome-wide association studies
HC	healthy control
IFIT1	interferon induced protein with tetratricopeptide repeats 1
IFN	interferon
IFN-a	interferon-alpha
IFN-g	interferon-gamma
IL-18	interleukin-18
IL-18R	interleukin-18 receptor
IL-18R1/IL-18Ra	interleukin-18 receptor alpha
IL18RAP/IL-18Rb	interleukin-18 receptor accessory protein/interleukin-18 receptor beta
IL-1R	interleukin-1 receptor
IQR	interquartile range
ISGs	interferon-stimulated genes
LDGs	low density-gradient granulocytes
LN	lupus nephritis
MAPK pathway	mitogen-activated protein kinase pathway
mtROS	mitochondrial reactive oxygen species
MyD88	myeloid differentiation primary response protein 88
NA	not available/not applicable
NADPH	nicotinamide adenine dinucleotide phosphate
NETs	neutrophil extracellular traps
NF-kB	nuclear factor kappa-light-chain-enhancer of activated B cells
NKcells	natural killer cells
NLN	non-nephritic lupus
PBMCs	peripheral blood mononuclear cells
PMA	phorbol-myristate acetate
qRT-PCR	real-time quantitative reverse transcription polymerase chain reaction
rhIL-18	recombinant human interleukin-18
RNP-IC	ribonucleoprotein immune complex
ROS	reactive oxygen species
RQ	relative quantity
SJIA	systemic-onset juvenile idiopathic arthritis
SLE	systemic lupus erythematosus
SLEDAI-2K	systemic lupus erythematosus disease activity index 2000
SLICC	Systemic Lupus International Collaborating Clinics
SNP	single nucleotide polymorphism
Th-1 cells	type 1 T helper cells
TIR	toll-interleukin-1 receptor
TLR	toll-like receptor