Table 3.
Correlations between P300 parameters and clinical symptoms.
Entire Subject a | ARMS (n = 33) | Schizophrenia (n = 39) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Amplitude (µV) | Latency (msec) | Amplitude (µV) | Latency (msec) | Amplitude (µV) | Latency (msec) | |||||||
rs | p | rs | p | rs | p | rs | p | rs | p | rs | p | |
JART | −0.03 | 0.77 | 0.08 | 0.44 | −0.08 | 0.65 | 0.07 | 0.71 | 0.10 | 0.56 | 0.01 | 0.95 |
PANSS: positive symptom | −0.15 | 0.20 | 0.02 | 0.86 | −0.08 | 0.68 | 0.05 | 0.78 | 0.12 | 0.47 | −0.11 | 0.50 |
negative symptom | −0.19 | 0.12 | 0.21 | 0.09 | −0.30 | 0.09 | 0.15 | 0.41 | −0.28 | 0.10 | 0.31 | 0.06 |
general psychopathology | −0.22 | 0.07 | 0.08 | 0.51 | −0.08 | 0.68 | 0.17 | 0.34 | −0.34 | 0.04 * | −0.022 | 0.90 |
mGAF | 0.46 | 0.003 ** | −0.14 | 0.29 | 0.48 | 0.02 * | 0.09 | 0.67 | 0.14 | 0.46 | −0.095 | 0.61 |
SCoRS | −0.22 | 0.07 | 0.17 | 0.16 | −0.11 | 0.54 | 0.16 | 0.36 | −0.17 | 0.33 | 0.11 | 0.52 |
BACS: verbal memory | 0.25 | 0.01 | −0.10 | 0.35 | 0.02 | 0.65 | −0.02 | 0.92 | 0.31 | 0.06 | −0.04 | 0.80 |
working memory | 0.21 | 0.04 | −0.19 | 0.06 | −0.21 | 0.23 | −0.15 | 0.40 | 0.28 | 0.10 | −0.12 | 0.48 |
motor function | 0.41 | <0.001 b | −0.22 | 0.04 | 0.03 | 0.86 | −0.28 | 0.10 | 0.27 | 0.10 | −0.14 | 0.54 |
verbal fluency | 0.28 | 0.007 | −0.24 | 0.02 | −0.03 | 0.87 | −0.17 | 0.34 | 0.17 | 0.31 | −0.85 | 0.62 |
attention | 0.50 | <0.001 b | −0.33 | 0.001 b | 0.06 | 0.74 | −0.16 | 0.36 | 0.43 | 0.01 | −0.24 | 0.14 |
executive function | 0.36 | 0.003 b | −0.15 | 0.14 | 0.06 | 0.74 | −0.002 | 0.99 | 0.37 | 0.03 | −0.20 | 0.22 |
BACS composite score | 0.43 | <0.001 ** | −0.28 | 0.006 * | 0.01 | 0.95 | −0.22 | 0.20 | 0.34 | 0.04 * | −0.16 | 0.33 |
Data were calculated by Spearman’s rank correlation (* p < 0.05, ** p < 0.01). a “Entire subject” means schizophrenia, ARMS, and healthy control (n = 100). As shown in Table 1, PANSS, mGAF and SCoRS were measured only in ARMS and schizophrenia patients (n = 72). b BACS subdomains survived after Bonferroni’s correction for multiple comparison.