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Inflammatory responses of mouse primary microglia cells in response to Au18 NCs. Primary microglia cells were treated with Au18 NCs (0.006 ppm, 0.6 ppm, 6.0 ppm) or lypopolysaccharyde (LPS) (125 ng/mL) and cultured during 3 h. The expression of interleukin 1-β (IL-1β), tumor necrosis factor (TNF-α) and Ym1/2 was examined using RT-qPCR (n = 3/group, * p < 0.05; *** p < 0.001 as compare to untreated cells).
