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. 2021 May 10;12:634839. doi: 10.3389/fphys.2021.634839

FIGURE 2.

FIGURE 2

Vaping contributes to increased pulmonary pathology in mice infected with MHV-A59. (A) Study design. (B) Lung wet/dry ratios of mice receiving either PBS (mock), vaped e-liquid, infection with MHV or vaped and infected with MHV (compared with mock). All lungs were harvested on day 12. n = 4 mice (two males and two females) per treatment group. (C) Viability study of vaped mice or mice infected with either MHV or vaped + infected with MHV (compared with mock). n = 4 mice (two males and two females) per group. The mock and vape-alone groups overlay each other so that the mock is not visible. ANOVA was performed to compare among different groups and compared with the mock control using Dunnett’s post hoc test. Symbols and bars represent the mean ± SEM compared with the mock control (*P < 0.05, **P < 0.01). N.S., not significant.