Figure 3.
Time-of-addition assay. The effects of baicalein and baicalin on SARS-CoV-2 in vitro replication were assessed at different time points of compound addition. A single concentration of each compound based on EC90 value of the compound was added to the respective wells from 2 h prior infection up to 10 h post infection. Data for each time point were analyzed independently to the virus control via two-way ANOVA analysis using GraphPad Prism 7 for Windows. The results are presented as means ± standard error whereby p < 0.01 was represented as **, p < 0.001 as *** and nonsignificant readings were labelled as ns.