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. 2021 Apr 22;13(5):728. doi: 10.3390/v13050728

Figure 5.

Figure 5

AHR after recovery from acute sublethal PVM infection. (a,b) Percent contraction observed in airways in response to increasing concentrations of carbachol (CCh) in precision-cut lung slices (PCLS) from uninfected mice and mice that recovered from an acute sublethal PVM infection; results on day 21 (a) and day 45 (b) are as shown; * p < 0.05, ** p < 0.01, 2-way ANOVA with Sidak’s post-hoc test; n = 5–8 mice per group. Sample data corresponding to (b) are shown in Supplemental Figure S1. (c) Total lung resistance (Rrs) observed in response to administration of increasing concentrations of nebulized methacholine (MCh) to uninfected mice and mice that had recovered from an acute sublethal PVM infection (day 21); * p < 0.05, ** p < 0.01, 2-way ANOVA with Sidak’s post-hoc test, n = 4–5 mice per group.