Figure 1.

Cystic fibrosis differs in factors affecting both oral and lung health. (a) Mean relative abundances of 15 most abundant genera in CF samples and matched controls. The remaining genera are grouped together and colored in white. (b) Two of the significantly differentially abundant genera are shown (centered log ratio values of Rothia and Treponema), as well as alpha diversity as calculated by the Shannon diversity index and the salivary pH. In the header of each boxplot, ‘Other effects’ refers to the significance of the fixed effects included in the calculations (antibiotic use, gender, age, and population). The label ‘none’ indicates that none of these had a significant effect on average for the given taxon or variable