Table 2.
Mycobacterium tuberculosis antibiotic resistance profiles in different provinces of Iran during 2013-2020
| Province | Antibiotic resistance (%) |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| First-line drugs | Second-line drugs | |||||||||||||
| INH | RIF | EMB | PZA | STR | PAS | CAP | CYC | ETO | OFX | KAN | AMK | MDR | XDR | |
| Ardabil | 11.9 | 8.9 | ND | 11.1 | ND | ND | ND | ND | ND | ND | ND | ND | 6.1 | ND |
| East Azerbaijan | 4.3 | 9.9 | 2.4 | 20.1 | 21 | ND | ND | ND | ND | ND | ND | ND | 8.3 | ND |
| Fars | 16.7 | 16.1 | 7.8 | ND | 10.5 | ND | ND | ND | ND | ND | ND | ND | 13.6 | ND |
| Golestan | 3.4 | 1.5 | 0 | ND | 7.3 | ND | ND | ND | ND | ND | ND | ND | 4.2 | ND |
| Guilan | 2.5 | 5.1 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | 7.6 | ND |
| Hamadan | 6.9 | 8.1 | ND | 40 | ND | ND | ND | ND | ND | ND | ND | ND | 0 | ND |
| Hormozgan | 8.2 | 6.1 | 4.1 | ND | 7.1 | ND | ND | ND | ND | ND | ND | ND | 6.7 | ND |
| Ilam | 14 | 8.4 | ND | 25 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| Isfahan | 6.2 | 3.7 | 2.7 | ND | 4.5 | ND | ND | ND | ND | ND | ND | ND | 3.2 | ND |
| Kerman | 4.1 | 12.5 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | 12.5 | ND |
| Kermanshah | 9.4 | 13.8 | 14.2 | 22.9 | 22.1 | 16.9 | ND | 3.5 | 12.5 | ND | ND | ND | 14.2 | ND |
| Khuzestan | 8.9 | 11.7 | 4 | ND | 36.3 | ND | ND | ND | ND | ND | ND | ND | 6.1 | ND |
| Kurdistan | 8.7 | 6.1 | ND | 11.1 | ND | ND | ND | ND | ND | ND | ND | ND | 0 | ND |
| Lorestan | 1.5 | 4.5 | ND | 21 | ND | ND | ND | ND | ND | ND | ND | ND | 3.5 | ND |
| Markazi | 7.4 | 6.3 | 6.9 | ND | 2.6 | ND | ND | ND | ND | ND | ND | ND | 8.6 | ND |
| Mazandaran | 3.8 | 5.1 | ND | ND | 7.4 | ND | ND | ND | ND | ND | 5.5 | 5.5 | 3.8 | ND |
| Qazvin | 9.4 | 6.1 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | 20 | ND |
| Qom | 4.9 | 4.9 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | 6.5 | ND |
| Razavi Khorasan | 7.4 | 7.4 | 5 | 0 | 4.6 | ND | ND | ND | ND | ND | ND | ND | 4.1 | ND |
| Semnan | 0 | 0 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | 0 | ND |
| Sistan and Balouchastan | 4.1 | 4.3 | 0.9 | ND | 1.4 | ND | ND | ND | ND | ND | ND | ND | 1.9 | ND |
| Tehran | 7.6 | 7.4 | 7.6 | ND | 14.7 | 1.1 | 1.7 | 1 | 10.7 | 1.5 | 3.3 | 1 | 5.8 | 0.9 |
| West Azerbaijan | 3.4 | 10.2 | ND | 30 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| Yazd | 0 | 8.3 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | 0 | ND |
| Zanjan | 0 | 0 | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND |
INH-isoniazid; RIF-rifampin; EMB-ethambutol; PZA-pyrazinamide; STR-streptomycin; PAS-para-aminosalicylic acid; CAP-capreomycin; CYC-cycloserine; ETO-ethionamide; OFX-ofloxacin; KAN-kanamycin; AMK-amikacin; MDR-multiple drug-resistant; XDR-extensively drug-resistant; ND-not determined