Skip to main content
. 2021 May 21;59(1):47. doi: 10.3892/ijo.2021.5227

Figure 2.

Figure 2

miR-153-3p inhibits the proliferation and promotes the apoptosis of RB cells. (A) RT-qPCR was performed to determine the expression levels of miR-153 following miR-153 mimic and miR-153 inhibitor transfection into WERI-RB-1 and Y79 cells. (B and C) Cell viability was measured using a CCK-8 assay following miR-153 mimic and miR-153 inhibitor transfection into WERI-RB-1 and Y79 cells. The results (mean ± SD) are from three independent experiments (*P<0.05, **P<0.01 vs. mimics NC). (D) Apoptosis of WERI-RB-1 and Y79 cells following transfection with miR-153 mimic or mimics NC was determined by flow cytometric analysis (**P<0.01 vs. mimics NC). (E) The expression of caspase-3 in WERB-RI-1 and Y79 cells following transfection with miR-153 mimic or mimics NC was detected by immunofluorescence (**P<0.01 vs. mimics NC). RB, retinoblastoma.