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. 2021 May 4;10:e64213. doi: 10.7554/eLife.64213

Figure 2. Summary of patient-derived model fibrosis with respect to RD inducibility.

Figure 2.

(A) Histogram of AFib (22/45) and ESUS (24/45) inducible patients. Inducibility was not significantly different by χ2 test. (B) Patients with ESUS and AFib arranged by percentage of LA fibrosis. Dotted lines indicate the quartiles of fibrosis observed for all 90 patient-derived models. Circles are indicative of stable reentry observed in the model from at least one pacing site after in silico pacing protocol. Triangles indicate no RDs after pacing from all 15 pacing sites independently. Cases that lacked RDs despite high fibrosis (inset I) or were inducible despite low fibrosis (inset II) are highlighted.

Figure 2—source data 1. Spreadsheet including source data underlying Figure 2.
ESUS and AFib patient ID numbers; inducibility status (i.e., whether RD-sustained arrhythmia was observed in the corresponding patient-specific LA model); and LA volumetric fibrosis burden (%) extracted directly from clinical report.