Table 3.
Effects of crude extract of H. abyssinica on castor oil-induced enteropooling
| Dose administered | Mean volume of small intestinal content (g) | % inhibition | Mean weight of small intestinal content (ml) | % inhibition |
|---|---|---|---|---|
| Control | 0.69 ± 0.09 | — | 0.76 ± 0.01 | — |
| 100 mg/kg | 0.66 ± 0.04b3 | 4.30 | 0.70 ± 0.02 | 7.89 |
| 200 mg/kg | 0.50 ± 0.02a2b2 | 27.60 | 0.57 ± 0.06a2 | 25.00 |
| 400 mg/kg | 0.38 ± 0.02a3 | 45.00 | 0.41 ± 0.02a3 | 46.00 |
| Loperamide 3 mg/kg | 0.36 ± 0.02a3 | 47.80 | 0.38 ± 0.02a3 | 50.00 |
Data are expressed as mean ± SEM (n = 6). aCompared to negative control. bCompared to loperamide 3 mg/kg. 1P < 0.05, 2P < 0.01, and 3P < 0.001. Negative controls received 10 ml/kg distilled water.