Table 4.
Dose administered | Delay in defecation time (Dfreq) (%) | Gut meal travel distance (Gmeq) (%) | Purging frequency in number of wet stools (%) | In vivoADI |
---|---|---|---|---|
Control | — | — | — | — |
100 mg/kg | 74.62 | 14.87 | 42.85 | 36.23 |
200 mg/kg | 126.20 | 29.20 | 55.71 | 59.00 |
400 mg/kg | 134.46 | 54.00 | 73.85 | 81.24 |
Loperamide 3 mg/kg | 189.45 | 67.10 | 77.50 | 99.48 |
ADI = antidiarrheal index.