Fig. 1.

Histogram of frequent mutations observed in the Brazilian SARS-CoV-2 genomes harboring E484K mutation. Red labels above the bars indicate absolute nucleotide position and the blue labels indicate effects of these mutations in the corresponding proteins. As P.1 has only 19 genomes represented and multiple mutations, only main mutations of concern were highlighted.

UTR: Untranslated region; Syn: Synonymous substitution; del: deletion; ORF: Open Reading Frame; Nsp: Non-structural protein; S: Spike; E: Envelope; M: Membrane; N: Nucleocapsid.