Figure 2.

CT scan of patients with mesenteric involvement by histiocytosis. Patient #11 (A) with mesenteric tumour (long arrows) surrounding mesenteric vessels, initially diagnosed as sclerosing mesenteritis. This patient had typical Erdheim-Chester lesions consisting in ‘coated aorta’ (short arrows) and ‘hairy kidneys’ (arrow heads). This patient also had intraperitoneal effusion in the parieto-colic area (star) and around the liver. Axial CT scan, contrast injection in portal phase. Patient #2 with mesenteric infiltration (arrows) before (B), and with partial response after 4.5 months of treatment with trametinib (C). Axial CT scan, without contrast injection. Patient #15 with mesenteric infiltration (arrows) in the pelvis, before (D) and after 7 months (E) and 39 months (F) of treatment with vemurafenib. Small lymph nodes were also present in this area. Axial CT scan, contrast injection.