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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Drug Metab Pharmacokinet. 2021 Jan 22;38:100384. doi: 10.1016/j.dmpk.2021.100384

Table 3.

Spearman’s correlation coefficients for the order of Ki or Km values among the five variants

Inhibitors (order of Ki values) Substrate (order of Km values)
Inhibitors FCZ KCZ VCZ ITCZ TST
FCZ 0.9 0.9 −0.1 0.98
KCZ 0.7 −0.2 0.49
VCZ −0.3 1.0
ITCZ 0.09