Table 2.

Studies using computer navigation-assisted UKA.

Author, year	Patients (conventional)	Patients (CN)	Navigation/Imaging system	Inclusion Criteria	Exclusion Criteria
Keene et al., 2006	10	10	Ci Preservation System (Munich, Germany)	•Bilateral medial compartment osteoarthritis awaiting bilateral simultaneous UKA	•Not reported
Jean-Yves Jenny 2008	30	•30: Conventional Open Navigated Technique •30: MIS Experimental Navigated Technique •30: MIS Navigation-dedicated Technique	Orthopilot Navigation System (B. Braun Aesculap, Tuttlingen Germany)	•Medial compartment osteoarthritis	•Not reported
Lim et al., 2009	21	30	Orthopilot Navigation System (B. Braun Aesculap, Tuttlingen Germany)	•Participate in low demand activities •Range of motion of at least 115° flexion •Less than 10° flexion contracture •Less than 10° of varus/valgus malalignment •Stable knee joint with absence of subluxation, varus or valgus thrust on ambulation •Minimal involvement of contralateral tibiofemoral and patellofemoral compartments •Absence of underlying tibiofemoral osseous pathology	•Not reported
Ollivier et al., 2016	30	30	Patient specific information using MRI protocol (Materialise™, Leuven, Belgium)	•Isolated symptomatic medial femorotibial knee arthritis •Varus deformity •Between 50 and 85 years of age •Acceptance of a new technology protocol (including delay between MRI and surgery)	•ROM below 0°–100° (extension to flexion) •Unstable knees in frontal and/or sagittal planes •Personal history of trauma, sepsis, tumor, inflammatory or skeletal disease (that could influence gait parameters) •Previous lower limb joint (ankle to hip) surgery that could lead to an artifact effect on imaging •Any contraindication to MRI
Zhang et al., 2016	41	40	Vector Vision Version 1.52 (BrianLAB, Munich, Germany)	•Pain in a single compartment secondary to osteoarthritis or necrosis •>60 years age •Weight <82 kg •Sedentary lifestyle •Range of motion >90° •Flexion contracture <5° •Angular deformities <10–15°	•Systemic or inflammatory arthritis •Knee instability or subluxation •Fixed flexion contracture •Loss of anterior or posterior cruciate ligaments •Intraoperative finding of eburnated bone in either the patella or the opposite compartment
Alvand et al., 2018	22	23	“Signature” System (Zimmer Biomet Inc, Warsaw, IN, USA)	•Both cruciate ligaments functionally intact •Full thickness cartilage in lateral compartment •Correctable intra-articular varus deformity (based on clinical assessment) •Full-thickness cartilage loss in the medial compartment	•Contraindications for MRI •All forms of inflammatory arthritis