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. 2021 Mar 1;28(6):1671–1687. doi: 10.1007/s43032-021-00496-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Induction of endometrial receptivity-related genes in BoTA-administered mouse uterus. Representative two images of immunohistochemistry analyses of integrin β3 (a) and OPN (b) in longitudinally sectioned mouse uterus harvested 8 days after BoTA intrauterine infusion. Saline-treated endometrium was used for control. For the negative control, mouse or rabbit IgG was used. Scale bar: 20um. QRT-PCR analysis of Lif (c), Stc1 (d), and Stc2 (e) in BoTA-treated uterus samples compared to controls. Comparison groups for (c–e) are from 3 independent experiments and analyzed using the unpaired Student t-test for parametric distributions including P-values (*<0.05, **<0.01, ***<0.001)