Fig. 1.

5′-Adenosine monophosphate-activated protein kinase (AMPK)-associated therapeutic effects of statins. DMED diabetes mellitus-induced erectile dysfunction, eNOS endothelial nitric oxide synthase, ER endoplasmic reticulum, FOXO3a Forkhead box O3, HIF-1a hypoxia-inducible factor-1 alpha, LKB1 liver kinase B1, mTOR mammalian target of the rapamycin complex, mTORC1 mechanistic target of rapamycin complex-1, SREBP1 sterol regulatory element binding protein‐1, TFEB transcription factor EB