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. 2021 Mar 1;121(6):1593–1606. doi: 10.1007/s00421-021-04626-3

Table 2.

Individual characteristics of low-, medium-, and high responders for resting Tre, ΔTre, WBSR and HR [mean ± SD or median (Q1, Q3)] with p values from analysis of variance

Resting Tre responders ΔTre responders
Low Medium High p Low Medium High p
Pre- to post-HA change§ (°C)

0.2

(0.0, 0.3)m,h

− 0.1

(− 0.2, − 0.1)l,h

− 0.5

(− 0.6, − 0.4)l,m

 < 0.001np

0.3

(0.2, 0.4)m,h

0.0

(0.0, 0.0)l,h

− 0.2

(− 0.3, − 0.2)l,m

 < 0.001np
Sex (no. male/female) 3/5 7/1 5/3 5/3 6/2 4/4
Age (y) 27 (24, 35) 32 (30, 36) 28 (26, 36) 0.6np 34 ± 7 27 ± 5 32 ± 10 0.2
Body mass (kg) 70.7 ± 7.2 78.7 ± 12.4 77.5 ± 10.8 0.3 77.3 ± 11.9 76.7 ± 7.9 72.8 ± 12.1 0.7
BSA (m2) 1.9 ± 0.1 2.0 ± 0.2 2.0 ± 0.2 0.3 2.0 ± 0.2 2.0 ± 0.1 1.9 ± 0.2 0.7
BSA-to-mass ratio (cm2 kg−1) 268 ± 13 258 ± 18 259 ± 18 0.4 256 ± 18 262 ± 11 268 ± 19 0.4
Body fat (%) 25 ± 7 18 ± 4 19 ± 4 0.04 19 ± 5 18 ± 5 24 ± 7 0.06
V˙O2peak,kg (mL kg−1  min−1) 46.3 ± 9.6 56.6 ± 6.1 52.7 ± 8.0 0.052 52.7 ± 7.0 56.2 ± 7.3 46.7 ± 10.0 0.09
Weekly exercise time× (min) 292 ± 117 385 ± 54 340 ± 166 0.4 406 ± 131 335 ± 115 275 ± 89 0.1
WBSR responders HR responders
Low Medium High p Low Medium High p

Pre- to post-HA change§

(g h−1/bpm)

70 (23, 84)m,h

250

(214, 279)l,h

455

(387, 652)l,m

 < 0.001np

− 4

(− 4, − 1)m,h

− 9

(− 10, − 7)l,h

− 17

(− 19, − 15)l,m

 < 0.001np
Sex (no. male/female) 3/5 5/3 7/1 7/1 3/5 5/3
Age (y) 30 ± 7 30 ± 8 34 ± 9 0.4 31 ± 8 32 ± 8 31 ± 8 0.9
Body mass (kg) 67.5 ± 7.3h 76.3 ± 9.3 83.0 ± 9.3l 0.006 83.4 ± 9.4h 74.2 ± 10.5 69.2 ± 6.8l 0.02
BSA (m2) 1.8 ± 0.1h 2.0 ± 0.2 2.1 ± 0.1l 0.02 2.1 ± 0.2h 1.9 ± 0.2 1.9 ± 0.1l 0.02
BSA-to-mass ratio (cm2 kg−1) 274 ± 15h 263 ± 12 249 ± 12l 0.005 252 ± 11 264 ± 19 270 ± 13 0.06
Body fat (%) 23 ± 6 19 ± 6 19 ± 4 0.3 18 ± 3 23 ± 7 20 ± 6 0.2
V˙O2peak,kg (mL kg−1 min−1) 49.9 ± 8.8 55.7 ± 9.5 50.0 ± 7.9 0.3 54.2 ± 6.4 48.2 ± 8.4 53.2 ± 11.0 0.4
Weekly exercise time× (min) 303 ± 95 332 ± 107 385 ± 154 0.4 375 ± 64 353 ± 163 290 ± 118 0.4

p values ≤ 0.050 are highlighted in bold

SD standard deviation, Q1 first quartile, Q3 third quartile, BSA body surface area, V˙˙O2peak,kg maximum oxygen uptake relative to body mass, Tre rectal temperature, ΔTre exercise-induced rise in rectal temperature, HR heart rate, WBSR whole-body sweat rate

npFrom non-parametric test

lSignificantly different from low responders (p ≤ 0.050)

mSignificantly different from medium responders (p ≤ 0.050)

hSignificantly different from high responders (p ≤ 0.050)

§Pre- to post-HA change was calculated as heat stress test 2 minus heat stress test 1

×swimming exercise excluded, n = 23