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. 2021 May 24;11:10761. doi: 10.1038/s41598-021-89592-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Flow chart summarizing types of tests conducted as part of our study, and numbers of actionable variants detected in each sub-group. 237 patients were analyzed by both cfDNA NGS and ddPCR, and of these tissue NGS data was available for 158 patients. 119 patients were analyzed by cfDNA NGS but not ddPCR; of these, 35 had tissue NGS data available.